Combination therapy with remdesivir and immunomodulators improves respiratory status in COVID-19: A retrospective studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% confidence interval Analysis Baricitinib baseline benefit body mass index combination therapy Concomitant contributed control group coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Day Diabetes Mellitus examined faster greater hazard ratio immunomodulator immunomodulators IMPROVE in both group independent investigated median outcome Oxygen administration Patient patients Prognostic factors Remdesivir respiratory recovery retrospective Retrospective study severity single-center study standard treatment supplemental oxygen survival synergistic therapy Tocilizumab tocilizumab. treated two group [DOI] 10.1002/jmv.28037 PMC 바로가기
Treatment Strategies and Perforation Rate of Acute Appendicitis During the Early Phase of the Covid-19 Pandemic: A Swedish Cohort StudyResearch article Published on 2022-12-012022-10-05 Journal: The Journal of surgical research [Category] 치료법, [키워드] 95% confidence interval Acute appendicitis Appendicitis association calculate Care Conservative management COVID-19 COVID-19 pandemic diagnosed early phase Frequency initial less multivariate logistic regression Odds ratio pandemic Patient patients hospitalized Perforation Perforation rate phase Rate receive resource Result risk severity single-center study South Strategy surgical Swedish Treatment Treatment strategies [DOI] 10.1016/j.jss.2022.07.007 [Article Type] Research article
Risk of preeclampsia in patients with symptomatic COVID-19 infectionResearch article Published on 2022-11-012022-10-05 Journal: Journal of gynecology obstetrics and human reprodu [Category] SARS, 진단, 치료기술, [키워드] 95% CI Analysis association COVID-19 COVID-19 infection CT scan diagnosed Frequency in both groups management moderate not significant nulliparous objective occurred Patient patients preeclampsia Pregnancy pregnant women Prevent recent Result risk RT-PCR SARS-CoV-2 sensitivity analysis single-center study subject symptomatic Vascular fetal growth restriction Vascular FGR virus was performed [DOI] 10.1016/j.jogoh.2022.102459 [Article Type] Research article
Humoral response to COVID-19 vaccination in MS patients on disease modifying therapy: Immune profiles and clinical outcomesArticle Published on 2022-11-012022-10-05 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술, [키워드] administration age anti-CD20 anti-CD20 therapy Anti-SARS-CoV-2 S antibody Antibody Response Antibody titer appear B-cell CD20 cell count Clinical outcome Cohort collected Comprehensive COVID-19 COVID-19 infection COVID-19 vaccination death demographic demonstrated diagnosed with COVID-19 died disease Disease modifying therapy effective enrolled female FIVE Follow-up healthy control healthy controls humoral Humoral immunity Humoral response ICU care Immune profile immunoglobulins incidence increased risk investigation less longitudinal Lymphocyte count Multiple multiple sclerosis outcome Patient preventing infection profile reduced required Responder response to vaccination Result retrospective SARS-CoV-2 spike sclerosis serum severe disease significantly lower single-center study therapy Treatment vaccinated against COVID-19 vaccination Vaccine [DOI] 10.1016/j.msard.2022.104079 [Article Type] Article
COVID-19 lockdown negatively impacted on adherence to denosumab therapy: incidence of non-traumatic fractures and role of telemedicineArticle Published on 2022-10-012022-11-15 Journal: Journal of Endocrinological Investigation [Category] 진단, [키워드] collected Compliance COVID-19 disease Effectiveness evaluated Evidence fragility Fragility fracture impacted incidence increasingly lockdown management Osteoporosis pandemic Patient patients patients evaluated Prevalence prevalent rebound Rebound fracture. receiving risk factor single-center study supported therapy undergo widespread [DOI] 10.1007/s40618-022-01820-8 PMC 바로가기
Complement and endothelial cell activation in COVID-19 patients compared to controls with suspected SARS-CoV-2 infection: A prospective cohort studyArticle Published on 2022-09-202022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] 30-Day mortality Activation Admission Analysis Bacterial Biomarker blood sample C5a cascade clinically suspected comparable complement complement system Concentration Control control group controls COVID-19 COVID-19 patient disease E-selectin elevated endothelial Endothelial cell endothelial cells Endothelium evaluate excluded females galectin-3 galectin-3. ICAM-1 ICU Inflammatory inflammatory condition Inpatient male non-infectious nonspecific occurred outcome Outpatient Patient Pneumonia presenting prospective cohort study recruited respiratory viral infections SARS-CoV-2 SARS-COV-2 infection SC5b-9 significantly significantly higher single-center study VCAM-1 [DOI] 10.3389/fimmu.2022.941742 PMC 바로가기
Genomic and Epidemiological Features of COVID-19 in the Novosibirsk Region during the Beginning of the PandemicArticle Published on 2022-09-142022-11-16 Journal: Viruses [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Analysis Asymptomatic B.1 B.1.1 center children conducted Contact COVID-19 D614G substitution diagnostic tests Epidemiology First wave Genome sequences had no highest individual isolate Lineage Medicine Mutation pandemic pangolin patients with COVID-19 Phylogenetic Phylogeny phylogeny. positive positive sample Protein Region retrospective Russia SARS-CoV-2 SARS-CoV-2 sequencing single-center study tested the SARS-CoV-2 the Spike variant [DOI] 10.3390/v14092036 PMC 바로가기
Factors affecting the serologic response to SARS-CoV-2 vaccination in patients with solid tumors: A prospective study고형암 환자에서 SARS-CoV-2 백신접종에 대한 혈청학적 반응에 영향을 미치는 요인: 전향적 연구Observational Study Published on 2022-09-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] addition affecting analyzed Anti-SARS-CoV-2 S antibody antibody level Antibody test baseline blood sample BNT162b2 Cancer Chemotherapy CLIA clinical feature clinical study collected CoronaVac CoronaVac. COVID-19 demographic determine diagnoses dose enzyme evaluate Factor first dose IgG antibody IgG level immunoassay in both groups inactivated men mRNA vaccine of BNT162b2 oncology Patient Patients with cancer positive preventive measure proportion Prospective Study Quantitative RBD receiving Receptor binding domain SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 PCR SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose Serologic response Sex significantly significantly higher single-center study solid tumor solid tumors vaccination Vaccine Vaccines virus spike protein was determined were excluded were measured [DOI] 10.1016/j.jiac.2022.05.021 PMC 바로가기 [Article Type] Observational Study
Independent predictors of in-hospital mortality and the need for intensive care in hospitalized non-critical COVID-19 patients: a prospective cohort studyObservational Study Published on 2022-08-012022-10-04 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] active cancer Admission albumin albumin level analysis baseline blood test Blood urea nitrogen build Care Characteristics classical clinical feature condition confidence interval coronavirus COVID-19 death demographic data demographics died evaluate Factor Features Hospitalized hospitalized patient ICU ICU care in-hospital mortality independent independent predictors infected with SARS-CoV-2 intensive care intensive care unit laboratory parameter Male sex Older age outcome Pandemics Patient performed predict Predictive predictor Probability prospective cohort study receiver recruited risk ROC SARS-CoV-2 significant variables single-center study sodium Sodium. Stratification stratified tested the patient underlying disease urea [DOI] 10.1007/s11739-022-02962-6 PMC 바로가기 [Article Type] Observational Study
Definition of factors associated with negative antibody response after COVID-19 vaccination in patients with hematological diseases혈액 질환 환자에서 코로나19 백신 접종 후 항체 음성 반응과 관련된 요인 정의Article Published on 2022-08-012022-09-12 Journal: Annals of Hematology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] active treatment addition age Analysis antibody Antibody Response AstraZeneca BNT162b2 BTK inhibitor CML Combination Concentration correlated COVID-19 COVID-19 vaccination Definition demonstrated disease Efficacy Factor had no hematological Hematological diseases/disorders high mortality knowledge leukemia lymphoid median age Moderna mRNA-1273 naïve negative antibody response neoplasm Neoplasms not correlated other disease other diseases Patient patient cohort positive positive response reduced response to vaccination ruxolitinib SARS-CoV-2 seroconversion. significantly single-center study Spike protein Surveillance the SARS-CoV-2 therapy treated Treatment vaccination was performed were measured women [DOI] 10.1007/s00277-022-04866-z PMC 바로가기 [Article Type] Article